ea0025s8.4 | Hormones and bone metabolism | SFEBES2011
Coleman Robert
There are increasing numbers of long-term survivors from breast cancer who will have received combination endocrine treatments alone or in addition to cytotoxic chemotherapy. As a result, many of these individuals are at increased risk of osteoporosis, largely because of the endocrine changes induced by treatment characterised by a reduction in the level of bioavailable oestradiol. The associated increase in bone turnover that accompanies cancer treatment induced bone loss (CT...